class="info-alert">『Your web browser does not support JavaScript, but it does not affect browsing through the rest of the web site.』
jump to main content

Industrial Technology Research Institute

:::

Novel Dual-Target Therapy for Glaucoma

Technology Overview

ITRI-E-(S)4046 is an innovative dual-target medication that offers glaucoma patients a safer and more efficient treatment alternative.
ITRI-E-(S)4046 is an innovative dual-target medication that offers glaucoma patients a safer and more efficient treatment alternative.

ITRI-E-(S)4046 is an innovative dual-target medication specifically developed to tackle the challenges associated with glaucoma, a condition often referred to as the "silent thief" of vision. By targeting both Rho-associated protein kinase (ROCK) and Myosin light chain kinase 4 (MYLK-4), this groundbreaking drug represents a significant advancement in effectively managing intraocular pressure (IOP) and preventing optic nerve damage. Through a synergistic approach that mitigates trabecular meshwork blockage and enhances aqueous humor drainage, ITRI-E-(S)4046 offers glaucoma patients a safer and more efficient treatment alternative.

Applications & Benefits

  • This innovative drug offers glaucoma patients enhanced efficacy in controlling intraocular pressure (IOP) and preventing optic nerve damage.
  • This innovation makes an advance in glaucoma treatment and is expected to drive the pharmaceutical industry to capture the niche market of ophthalmic drugs.

Contact

Dr. Chiu-Lien Hung (Joy)
joyhung@itri.org.tw

The novel dual-target therapy developed by ITRI provides glauoma patients with a safer and more effective tratment option, addressing the need for diverse mechanisms of action and better safety profiles in glaucoma management.

One-Stop Biomedical Services


One-Stop Biomedical Services

  • Listing Regulations Consulting: FDA/TFDA/CE application, medical device verification/export, medical device/medicine registration, IRB document organization, clinical trial application, and more.
  • Technology Transfer: Bio-IT, diagnostics and precision medicine technology, regeneration medicine technology, natural medicine and healthcare technology, targeted drug and delivery technology.
  • Model Translation: Domestic supply chain linkage, medical device design control, market analysis, strategy analysis of regulation in commercialization, and more.
  • Preclinical / Clinical Trial: Functional safety assessments, clinical research organization linkage, clinical evaluation and analysis, clinical trial planning, clinical trial analysis and reports.
  • Other Services: Quality system consulting, commercialization consulting, smart health solutions, software validation, medical device risk management, information security risk evaluation, technical documents preparation, business ecosystem linkage, and more.