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Industrial Technology Research Institute

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HYA-HEAL+: Where Science Meets Beauty

Technology Overview

HYA-HEAL+ Limited Edition Anti-Aging Essentials Set.
HYA-HEAL+ Limited Edition Anti-Aging Essentials Set.

ITRI has developed a patented technology, HYA-HEAL+, which effectively inhibits enzymatic activity to prevent the breakdown of skin collagen. Its active molecules help protect collagen, restoring the skin’s firmness and radiant glow. This innovative technology was awarded the Certificat d'Excellence by Cosmetic Valley France.

Matrix metalloproteinases (MMPs) are enzymes that degrade collagen in the dermis. When collagen regeneration cannot keep pace with collagen loss, the dermal structure begins to collapse, resulting in the formation of wrinkles.

HYA-HEAL+ skin care technology, formulated with low molecular weight hyaluronic acid, helps protect collagen from MMP-induced degradation and is easily absorbed into the skin to enhance its effectiveness.

Applications & Benefits

The collagen regenerative technology has successfully supported the launch of a startup company and secured patents in multiple countries. It has also been recognized by the International Cosmetics Association and has received several international awards. ITRI continues to develop various formulations for use in lotions, serums, creams, eye creams, and makeup.

Beyond cosmetic applications, this active ingredient is also well-suited for post-laser treatment skincare and use in gels and ointments for chronic wound care. It helps strengthen the skin barrier, lock in moisture, and promote blood vessel formation and wound healing.

Ultrasound tests showed that after 28 days of use, collagen increased by over 30%. Skin became firmer, and density improved by up to 19.6%.
Ultrasound tests showed that after 28 days of use, collagen increased by over 30%. Skin became firmer, and density improved by up to 19.6%.