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工業技術研究院

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技術名稱: 生物觸媒及應用技術

技術簡介

以固定化2-epimerase及固定化aldolase將基質N-acetyl-glucosamine(GluNAc)及Pyruvate (Na)一起反應。不同於國外以鹼催化GluNAc反應轉化成ManNAc之製程。

Abstract

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技術規格

以雙固定化2-epimerase及aldolase將基質N-acetyl-glucosamine(GluNAc)及Pyruvate (Na) 於反應溫度30℃條件下一起反應,反應時間24小時,可得Sialic acid對GluNAc反應收率為35﹪,經回收可得純度95﹪產品。

Technical Specification

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技術特色

以雙固定化2-epimerase及aldolase反應生產Sialic acid。

應用範圍

酵素觸媒催化有機合成反應製造各種精密化學品

接受技術者具備基礎建議(設備)

接受技術者具備基礎建議(專業)

生化及醫藥製造業及生化

技術分類 醫藥化學品

聯絡資訊

聯絡人:李志忠 藥效與藥動研究室

電話:+886-3-5732904 或 Email:TzeChungLee@itri.org.tw

客服專線:+886-800-45-8899

傳真:+886-3-5732359

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