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工業技術研究院

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技術名稱: 自動化生物晶片雜交儀平台

技術簡介

結合生醫中心之晶片實驗標準流程與機械所自動化專長,目前發展之自動化晶片雜交儀雛型儀,其設計概念將”自動化”涵蓋整個晶片雜交實驗,此雛型機亦具備高通量潛力(>48片/天之處理能力)與開放式晶片平台設計(適用於1x3大小的晶片)。使用者只需將欲雜交之基因晶片以及製備好之雜交樣品置入雛型機中,即可等待完成雜交之晶片退出,即可進行掃描,無需將樣品注入等動作,與目前市場上之晶片雜交儀有很大的區別,藉此提高實驗再現性,同時達到降低成本的目的。

Abstract

The ITRI robotic hybridization station is a fully automated and high throughput biological sample injection, microarray hybridization and washing system. It is designed to handle at the maximum of 48 1x3 glass arrays/samples with minimum requirement of robotic devices. The machine‘s modular design allows convenient individual component replacement which makes the expansion of system capacity easily. Users only do two things, array and sample loading, before getting the slides ready to scan for the hybridization results. Further more, hybridization experiments can be added at anytime without interrupting the ongoing ones.

技術規格

高通量晶片處理能力; 完全自動化; 開放式平台設計。

Technical Specification

fully automated and high throughput biological sample injection, microarray hybridization and washing system

技術特色

由於晶片實驗人為操作造成之誤差影響實驗結果甚鉅,因此為要求精確結果以及符合未來臨床診斷用之基因晶片市場所需,自動化雜交平台為必然趨勢。然由於是受之自動化雜交儀並非達到”完全自動化”的效率,且實驗結果並不如預期佳,因此改良設計後的「自動化生物晶片雜交儀平台」則可符合以上要求,具有完全自動化,高通量晶片處理能力並且為開放式平台,不僅可搭配DNA基因晶片亦可使用蛋白質晶片等產品。

應用範圍

符合1*3大小之玻璃/塑膠晶片,DNA晶片或者蛋白質晶片皆可。

接受技術者具備基礎建議(設備)

機械製造

接受技術者具備基礎建議(專業)

自動化技術

技術分類 藥物治療

聯絡資訊

聯絡人:陳廷碩 體外診斷醫材技術組

電話:+886-3-5912143 或 Email:CTS@itri.org.tw

客服專線:+886-800-45-8899

傳真:+886-3-5912444

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