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工業技術研究院

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技術名稱: 低溫電鏡分析技術(包含樣品前處理與顯像與粒徑分析)

技術簡介

本技術結合新穎低溫電鏡設備、先進低溫樣品製備與傳輸技術、低劑量顯微影像拍攝技術與對比強化分析技術,可針對生醫藥載材料進行微結構分析

Abstract

the cryo-EM technical developments, including the build of cryo-EM equipment, sample preparation, cryo-transfer model, Low Dose model and contrast enhancement model. Our analysis technique has provided an efficient solution to characterize the microstructure of polymer and biomaterial.

技術規格

操作溫度:-177℃、觀測電壓:120、200kV

Technical Specification

Operating temperature :-177℃;Voltage:120 and 200 Kv

技術特色

快速低溫冰封冷凍樣品,可避免樣品因乾燥產生形變,真實呈現樣品於水溶液中的情形。

應用範圍

藥載材料(Liposome、micelles等)、蛋白質藥物

接受技術者具備基礎建議(設備)

冷凍衝頭裝置(CP3)

接受技術者具備基礎建議(專業)

材料、生醫

技術分類 材料分析

聯絡資訊

聯絡人:羅聖全 前瞻材料基磐技術組

電話:+886-3-5915296 或 Email:alexsclo@itri.org.tw

客服專線:+886-800-45-8899

傳真:+886-3-5910086

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