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工業技術研究院

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技術名稱: 口服peptide多層包覆藥物傳輸技術

技術簡介

利用口服多層膜包覆peptide藥物技術,保持peptide藥物於胃腸道之活性,延長胜?藥物於小腸滯留時間,並經由載體將peptide藥物遞送過小腸壁,達到有效胜?藥物之血液濃度。

Abstract

The multiple layers delivery technology maintained the bioactivity and prolonged the residue time of the peptide in the gastrointestinal tract which provided the oral formulation of the peptide drugs. The carrier delivered the peptide pass through the intestinal wall and achieved the therapeutic peptide plasma concentration in vivo.

技術規格

藥含量:20 mg/g - 60 mg/g 口服生體可利用率:8%

Technical Specification

Drug loading: 20 mg/g - 60 mg/g Bioavailability: 8%

技術特色

將以peptide口服劑型取代現有之peptide注射劑型,降低病患注射之不適感。

應用範圍

骨質疏鬆症、前列腺癌、糖尿病、肢端肥大症等

接受技術者具備基礎建議(設備)

減壓濃縮機、均質機、凍乾機、離心機等

接受技術者具備基礎建議(專業)

劑型、化工、藥物動力學等

技術分類 分子診斷

聯絡資訊

聯絡人:劉佳雯 標靶藥物技術中心

電話:+886-3-5743989 或 Email:cwliu@itri.org.tw

客服專線:+886-800-45-8899

傳真:+886-3-5732372

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