Industrial Technology Research Institute

Technology Overview

Bugu-M is a natural ingredient derived from multiple plant extracts, using raw materials registered in the Full List of Raw Materials Available for Food of the Ministry of Health and Welfare in Taiwan. Animal studies have shown that Bugu-M can improve memory, decrease the harmful effects of amyloid-β protein on neurons, and promote nerve neurotransmission-related protein expression, making it suitable for preventing and alleviating cognitive impairment as well as maintaining brain health and clear thoughts.

• Features
  • CMC
  • PD & Toxicology
  • AI-driven omics data analysis
• Specifications
  • Three animal models to assess cognitive function (Aß injection in rats and mice, 3xTg-AD mice)
  • Repeated dose 28-day oral toxicity study in rats
  • Application to prevent and ameliorate cognitive impairment

Applications & Benefits

• Healthcare industry

One-Stop Biomedical Services

• Listing Regulations Consulting: FDA/TFDA/CE application, medical device verification/export, medical device/medicine registration, IRB document organization, clinical trial application, and more.
• Technology Transfer: Bio-IT, diagnostics and precision medicine technology, regeneration medicine technology, natural medicine and healthcare technology, targeted drug and delivery technology.
• Model Translation: Domestic supply chain linkage, medical device design control, market analysis, strategy analysis of regulation in commercialization, and more.
• Preclinical/Clinical Trial: Functional safety assessments, clinical research organization linkage, clinical evaluation and analysis, clinical trial planning, clinical trial analysis and reports.
• Other Services: Quality system consulting, commercialization consulting, smart health solutions, software validation, medical device risk management, information security risk evaluation, technical documents preparation, business ecosystem linkage, and more.