Technology Overview
Artificial Ligament for Tissue Repairing
The global anterior cruciate ligament repair market is predicted to reach US$ 9.5 billion at 2028. Today, artificial ligament products are designed as mechanical prostheses without considering biological requirements. Inert PET material has been chosen for its stability. Consequently, clinical study results show a 31% rupture rate at 9.5 years post-implantation surgeries.
To solve this problem, ITRI's Artificial Ligament for Tissue Repairing Technology adopts the concept of tissue engineering scaffolds and utilizes composite-material fibers, composite textile structures, and cell-affinity surface treatment technology to develop a novel artificial ligament with both high mechanical strength and tissue repair function. Animal studies revealed better bone integration and ligament fixation strength as well. Moreover, soft tissue can grow onto and wrap around the fibers to protect them from abrasion. Besides, tissue on these fibers will further undergo ligamentization.
Features & Specifications
- Features
- Biopolymer/ceramic composite material enhancing bone integration
- Different cross section fiber increasing surfaces for cell attachment
- Composite textile structure with high mechanical strength allowing cell growth
- Surface treatment technology enhancing cell affinity
- Specifications
- Promote tissue repairing, and meanwhile meet the high mechanical strength requirement of ligament prosthesis
- Allows soft tissue growing onto and clading fibers to protect fibers from abrasion. Beside, tissue on these fiber would furtherly undergo ligamentization, therefore contributing to recover ligament function
- Enhance bone integration and increase ligament fixation strength
Applications & Benefits
Artificial ligament for tissue repairing utilizes composite material, composite textile structures and cell-affinity surface treatment technology. Each of these technologies can be further developed for different application.
- Composite material can be applied for orthopedic implants for better bone integration.
- Composite textile structures are suitable for textile medical devices, such as mesh and tissue engineering scaffold.
- Cell-affinity surface treatment technology can promote tissue repair of medical implants.
Contact
One-Stop Biomedical Services
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